DETAILLIERTE HINWEISE ZUR WIE VIEL KOSTET PENTOBARBITAL

Barbiturates appear to enhance the metabolism of exogenous corticosteroids probably through the induction of hepatic microsomal enzymes. Patients stabilized on corticosteroid therapy may require dosage adjustments if barbiturates are added to or withdrawn from their dosage regimen.The barbiturates are nonselective central nervous system depressants